Serveur d'exploration sur les relations entre la France et l'Australie

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AUSDRISK: an Australian Type 2 Diabetes Risk Assessment Tool based on demographic, lifestyle and simple anthropometric measures

Identifieur interne : 007A67 ( Main/Exploration ); précédent : 007A66; suivant : 007A68

AUSDRISK: an Australian Type 2 Diabetes Risk Assessment Tool based on demographic, lifestyle and simple anthropometric measures

Auteurs : LEI CHEN [Australie] ; Dianna J. Magliano [Australie] ; Beverley Balkau [Australie] ; Stephen Colagiuri [France] ; Paul Z. Zimmet [Australie] ; Andrew M. Tonkin [Australie] ; Paul Mitchell [Australie] ; Patrick J. Phillips [Australie] ; Jonathan E. Shaw [Australie]

Source :

RBID : Pascal:10-0134120

Descripteurs français

English descriptors

Abstract

Objective: To develop and validate a diabetes risk assessment tool for Australia based on demographic, lifestyle and simple anthropometric measures. Design and setting: 5-year follow-up (2004-2005) of the Australian Diabetes, Obesity and Lifestyle study (AusDiab, 1999-2000). Participants: 6060 AusDiab participants aged 25 years or older who did not have diagnosed diabetes at baseline. Main outcome measures: Incident diabetes at follow-up was defined by treatment with insulin or oral hypoglycaemic agents or by fasting plasma glucose level ≥ 7.0 mmol/L or 2-hour plasma glucose level in an oral glucose tolerance test ≥ 11.1 mmol/L. The risk prediction model was developed using logistic regression and converted to a simple score, which was then validated in two independent Australian cohorts (the Blue Mountains Eye Study and the North West Adelaide Health Study) using the area under the receiver operating characteristic curve (AROC) and the Hosmer-Lemeshow (HL) χ2 statistic. Results: 362 people developed diabetes. Age, sex, ethnicity, parental history of diabetes, history of high blood glucose level, use of antihypertensive medications, smoking, physical inactivity and waist circumference were included in the final prediction model. The AROC of the diabetes risk tool was 0.78 (95% CI, 0.76-0.81) and HL χ2 statistic was 4.1 (P=0.85). Using a score ≥ 12 (maximum, 35), the sensitivity, specificity and positive predictive value for identifying incident diabetes were 74.0%, 67.7% and 12.7%, respectively. The AROC and HL χ2 statistic in the two independent validation cohorts were 0.66 (95% CI, 0.60-0.71) and 9.2 (P=0.32), and 0.79 (95% CI, 0.72-0.86) and 29.4 (P < 0.001), respectively. Conclusions: This diabetes risk assessment tool provides a simple, non-invasive method to identify Australian adults at high risk of type 2 diabetes who might benefit from interventions to prevent or delay its onset.


Affiliations:


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Le document en format XML

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<name sortKey="Phillips, Patrick J" sort="Phillips, Patrick J" uniqKey="Phillips P" first="Patrick J." last="Phillips">Patrick J. Phillips</name>
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<name sortKey="Colagiuri, Stephen" sort="Colagiuri, Stephen" uniqKey="Colagiuri S" first="Stephen" last="Colagiuri">Stephen Colagiuri</name>
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<s2>Villejuif</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
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<country>France</country>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>University Paris-Sud</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
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<name sortKey="Zimmet, Paul Z" sort="Zimmet, Paul Z" uniqKey="Zimmet P" first="Paul Z." last="Zimmet">Paul Z. Zimmet</name>
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<s3>AUS</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
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<orgName type="university">Université de Sydney</orgName>
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<name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M." last="Tonkin">Andrew M. Tonkin</name>
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<country>Australie</country>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
<orgName type="university">Université de Sydney</orgName>
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<country>Australie</country>
<wicri:noRegion>Adelaide, SA</wicri:noRegion>
</affiliation>
</author>
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<name sortKey="Phillips, Patrick J" sort="Phillips, Patrick J" uniqKey="Phillips P" first="Patrick J." last="Phillips">Patrick J. Phillips</name>
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<s1>Baker IDI Heart and Diabetes Institute</s1>
<s2>Melbourne, VIC</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Baker IDI Heart and Diabetes Institute</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Shaw, Jonathan E" sort="Shaw, Jonathan E" uniqKey="Shaw J" first="Jonathan E." last="Shaw">Jonathan E. Shaw</name>
<affiliation wicri:level="1">
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<s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
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<sZ>1 aut.</sZ>
<sZ>9 aut.</sZ>
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<country>Australie</country>
<wicri:noRegion>Melbourne, VIC</wicri:noRegion>
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<title level="j" type="main">Medical journal of Australia</title>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Anthropometry</term>
<term>Australia</term>
<term>Life style</term>
<term>Public health</term>
<term>Quantitative analysis</term>
<term>Risk</term>
<term>Risk factor</term>
<term>Tool</term>
<term>Type 2 diabetes</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Diabète de type 2</term>
<term>Australie</term>
<term>Facteur risque</term>
<term>Risque</term>
<term>Outil</term>
<term>Santé publique</term>
<term>Mode de vie</term>
<term>Anthropométrie</term>
<term>Analyse quantitative</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr">
<term>Australie</term>
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<front>
<div type="abstract" xml:lang="en">Objective: To develop and validate a diabetes risk assessment tool for Australia based on demographic, lifestyle and simple anthropometric measures. Design and setting: 5-year follow-up (2004-2005) of the Australian Diabetes, Obesity and Lifestyle study (AusDiab, 1999-2000). Participants: 6060 AusDiab participants aged 25 years or older who did not have diagnosed diabetes at baseline. Main outcome measures: Incident diabetes at follow-up was defined by treatment with insulin or oral hypoglycaemic agents or by fasting plasma glucose level ≥ 7.0 mmol/L or 2-hour plasma glucose level in an oral glucose tolerance test ≥ 11.1 mmol/L. The risk prediction model was developed using logistic regression and converted to a simple score, which was then validated in two independent Australian cohorts (the Blue Mountains Eye Study and the North West Adelaide Health Study) using the area under the receiver operating characteristic curve (AROC) and the Hosmer-Lemeshow (HL) χ
<sup>2</sup>
statistic. Results: 362 people developed diabetes. Age, sex, ethnicity, parental history of diabetes, history of high blood glucose level, use of antihypertensive medications, smoking, physical inactivity and waist circumference were included in the final prediction model. The AROC of the diabetes risk tool was 0.78 (95% CI, 0.76-0.81) and HL χ
<sup>2</sup>
statistic was 4.1 (P=0.85). Using a score ≥ 12 (maximum, 35), the sensitivity, specificity and positive predictive value for identifying incident diabetes were 74.0%, 67.7% and 12.7%, respectively. The AROC and HL χ
<sup>2</sup>
statistic in the two independent validation cohorts were 0.66 (95% CI, 0.60-0.71) and 9.2 (P=0.32), and 0.79 (95% CI, 0.72-0.86) and 29.4 (P < 0.001), respectively. Conclusions: This diabetes risk assessment tool provides a simple, non-invasive method to identify Australian adults at high risk of type 2 diabetes who might benefit from interventions to prevent or delay its onset.</div>
</front>
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<li>Australie</li>
<li>France</li>
</country>
<region>
<li>Nouvelle-Galles du Sud</li>
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<settlement>
<li>Sydney</li>
</settlement>
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<noRegion>
<name sortKey="Lei Chen" sort="Lei Chen" uniqKey="Lei Chen" last="Lei Chen">LEI CHEN</name>
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<name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name>
<name sortKey="Magliano, Dianna J" sort="Magliano, Dianna J" uniqKey="Magliano D" first="Dianna J." last="Magliano">Dianna J. Magliano</name>
<name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<name sortKey="Phillips, Patrick J" sort="Phillips, Patrick J" uniqKey="Phillips P" first="Patrick J." last="Phillips">Patrick J. Phillips</name>
<name sortKey="Shaw, Jonathan E" sort="Shaw, Jonathan E" uniqKey="Shaw J" first="Jonathan E." last="Shaw">Jonathan E. Shaw</name>
<name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M." last="Tonkin">Andrew M. Tonkin</name>
<name sortKey="Zimmet, Paul Z" sort="Zimmet, Paul Z" uniqKey="Zimmet P" first="Paul Z." last="Zimmet">Paul Z. Zimmet</name>
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<country name="France">
<noRegion>
<name sortKey="Colagiuri, Stephen" sort="Colagiuri, Stephen" uniqKey="Colagiuri S" first="Stephen" last="Colagiuri">Stephen Colagiuri</name>
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   |texte=   AUSDRISK: an Australian Type 2 Diabetes Risk Assessment Tool based on demographic, lifestyle and simple anthropometric measures
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